My experience with straight feverfew was that my tongue went numb and stayed that way for a couple of years. (I was having migraines because I didn't know there were things I absolutely should not eat and the accumulated neurotoxicity from incomplete digestion was getting drastically bad. Treating migraine was not the correct thing to do in my case.)

Migraines as "regulatory system is screaming" has some support as I understand it. Which is nice and all but it'd be great if it would produce some useful treatment options.

Oh, and caffeine; live long enough and sometimes it turns out to be a Very Bad Idea; migraines, disorientation, loss of balance... Why? Nobody has the least idea. I'm pretty sure there are more such substances and no one has a clear idea of which or why or how often because it's only clinically noticeable in the caffeine case because caffeine addiction is a cultural norm so the baseline is hundreds of millions of people.